Atypical Mpox in Nepal

Vaccination and pre-departure education among Nepali travellers can prevent outbreaks.

On June 18, 2025, a 37-year-old male, who had recently returned from Saudi Arabia, was admitted to Sukraraj Tropical and Infectious Disease hospital with the complaints of rash, fever and lethargy. The following day, a polymerase chain reaction (PCR) test confirmed that he had the Mpox virus. This is the first reported Mpox case in Nepal in 2025. Previously, Nepal reported three instances of Mpox, two of which involved Nepali citizens who had also returned from Saudi Arabia. This case, however, was clinically different from the previous cases.