Breakthrough Covid-19 wave in Nepal

It is difficult to predict the outcome of the current breakthrough. Careful monitoring is essential.

There has been a gradual rise in the number of breakthrough Covid-19 cases across Nepal for the first time in several months. According to the United States Centres for Disease Control and Prevention (CDC), a vaccine breakthrough infection/case is defined as the detection of SARS-CoV-2 RNA or antigen in a respiratory specimen collected from a person more than 14 days after receipt of all recommended doses of an FDA-authorised Covid-19 vaccine. For a couple of days, I have been treating and advising several patients who tested positive for SARS-CoV-2 and have received their three recommended doses (including the first booster dose). This means that for the first time, large breakthrough Covid-19 wave is being observed/will likely be experienced further in the coming days in Nepal.